University of Florida, Department of Animal Sciences

Mateescu's Animal Genetics and Genomics Lab

Gastrointestinal nematode infections are the most pervasive problem currently facing the small ruminant production. The situation of anthelmintic resistance in sheep and goat farms has exceeded the control capacity of U.S. producers. In addition to technical support schemes for diagnostic, it is important to implement genetic selection programs to identify superior resistant animals to gastrointestinal nematode infections and reduce the dependence on anthelmintic treatment. Unless these strategies are implemented for producers, the negative effects of anthelmintic resistance on small ruminant farming in U.S. will continue to be detrimental.

Our research group focuses on identifying genetic markers for a sustainable and practical management systems in sheep and goat population, including the Florida Native sheep populations, to control gastrointestinal nematode infections.

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Article published in the Journal of Animal Science by Zaira Estrada. 2019

Estrada-Reyes Z.M., O. Rae, M.B. Jimenez Medrano, GJ.D. Leal-Gutiérrez, and R.G. Mateescu.

Association study reveals Th17, Treg and Th2 loci related to resistance to Haemonchus contortus in Florida Native sheep.

J. Anim. Sci. 97(11):4428-4444

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Article published in BMC Genomics by Zaira Estrada. 2019

Estrada-Reyes Z.M., Y. Tsukahara, R.R. Amadeu, A.L. Goetsch, T.A. Gipson, T. Sahlu, R. Puchala, Z. Wang, S.P. Hart, and R.G. Mateescu.

Signatures of selection for resistance to Haemonchus contortus in sheep and goats.

BMC Genomics. (2019)20:735

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Article published in the Livestock Science Journal by Zaira Estrada. 2019

Estrada-Reyes Z.M., Y. Tsukahara, A.L. Goetsch, T.A. Gipson, T. Sahlu, R. Puchala, and R.G. Mateescu.

Association analysis of immune response loci related to Haemonchus contortus exposure in sheep and goats using a targeted approach.

Livestock Science. 228:109-119

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Article published in the Parasite Immunology Journal by Zaira Estrada.

SARE grant awarded to graduate student Zaira Estrada

Graduate student Zaira Estrada Reyes has been awarded a Southern Sustainable Agriculture Research & Education (SARE) graduate student grant for her work on Genetic Markers for Resistance to Gastrointestinal Nematode Infections for a Sustainable Florida Native Sheep Production. Zaira's grant was one of 13 selected from 180 applications.

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